Babysitters of the Brain: Gial Cells in Health and Disease of the Nervous System: Babysitters on the Brain: Glial Cells in Health and Disease of the Nervous System

Neuroscience research has historically focused on the function of neurons, but recent discoveries have revealed fascinating roles of the other residents of the central nervous system: glial cells. Glial cells – often overlooked as “background actors” in the brain – serve crucial roles as protectors (microglia), supporters (astroglia), and insulators (oligodendroglia). Through short lectures, student-led journal clubs, and literature reviews, this seminar will explore unique populations of glial cells and their many essential functions, focusing on current data and unanswered questions. How do different glial cell populations support central nervous system development? In what ways do glia contribute to neural plasticity and repair throughout life? What are the roles of glial cells in neurological diseases such as Down syndrome, multiple sclerosis, and Alzheimer’s disease? We will explore these questions with emphasis on building experimental design skills and critical reading of primary literature, as well as the relevance of glial research to understanding nervous system health and disease.